secretory granules การใช้

• Endogenous heparin is localized and stored in secretory granules of mast cells.
• It is present in islet beta cell secretory granules.
• The secretory granules are also stored in packets along the axon called Herring bodies.
• Upon stimulation by the hypothalamus, secretory granules release said hormones into the bloodstream.
• Insulin granules are secretory granules, which can release their contents from the cell into the bloodstream.
• The remainder of the cell's cytoplasm is occupied by membrane-bound secretory granules containing mucin.
• Within cells, carboxypeptidase E is present in the secretory granules along with its peptide substrates and products.
• While at Yale, Farquhar s research focused on secretory granule membranes that merge with cell membranes during exocytosis.
• Inclusion bodies or secretory granules were not visualised on transmission electron microscopy within the cytoplasm of the villous enterocytes.
• Additionally, in the anterior pituitary, relatively high amounts of these subunits were found in growth hormone secretory granules.
• First, P-selectin is synthesized by megakaryocytes and endothelial cells, where it is sorted into the membranes of secretory granules.
• The epithelium of the A zone is composed of tall columns of secretory cells of a single type, packed with secretory granules.
• These materials are absorbed into secretory granules within the Golgi apparatus before being transported to the cell membrane and secreted into the extracellular environment.
• In the brain, Rab18 has been isolated in association with synaptic vesicles and has been observed to localise to secretory granules in neuroendocrine cells.
• Biosynthesized as precursors possessing an anionic, N-terminal proregion, cryptdins are packaged into the apically-directed secretory granules of Paneth cells.
• This work yielded the first description of crinophagy, the process by which secretory granules are taken up and disposed of in multivesicular bodies and lysosomes.
• Equimolar amounts of C-peptide and insulin are then stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation.
• This is stored with insulin in secretory granules in B cells and is co secreted with insulin " . ( Rang and Dale's Pharmacology, 2015 ).
• It has been proposed that membrane-associated carboxypeptidase E acts as a trans-Golgi network of the pituitary and in secretory granules; regulated secretory proteins are mostly hormones and neuropeptides.
• Insulin granules mature in three steps : ( 1 ) the lumen of the granule undergoes acidification, due to the acidic properties of a secretory granule; ( 2 ) proinsulin becomes insulin through the process of proteolysis.